Studies in Non-Specific Complement Fixation. I. Non-Specific Complement Fixation by Normal Rabbit Serum

Complement-fixation test for lymphogranuloma venereum in non-specific urethritis.

A report by Bedson (1950) had not shown such an association, nor was any such relationship noted between non-specific urethritis and the results of the complement-fixation test for enzootic abortion in ewes by Willcox and Stamp (1953). In the latter investigation some 323 complementfixation tests for enzootic abortion in ewes were performed on sera from 123 patients with present or past non-spe...

Studies on Complement Fixation

It is shown by complement fixation studies with protein antigens and specific immune rabbit sera that the rate of fixation of complement is determined by the concentration of antibodies in the immune sera, that the greater part of fixation of complement takes place during the 1st hour, and that fixation is practically completed at the end of 4 hours at ice box temperature. It is further shown t...

Indirect Complement Fixation in Foot-and-Mouth Disease

The Relation of Certain Bacteria to Non-specific Reactions with the Complement Fixation Test for Lues

Several investigators who have had a large experience with the complement fixation test for lues have called attention to the development in sera of anticomplementary bodies which cause inhibition of hemolysis in both the antigen and control tubes, and they have found that in most instances this property of the serum is lost after heating it for half an hour at 560 C. In some instances, however...

Studies on Complement Fixation in Tuberculosis. Iii

The prolonged extraction of the tubercle bacillus with boiling ethyl alcohol, followed by one or more reprecipitations by chilling the hot alcoholic solution, easily yields a preparation very active as antigen in the complement fixation reaction. This preparation gives a precipitation reaction with high dilution of the normal blood serum of a number of species. The precipitation reaction presen...